Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation

Merzenich. (1983). Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation.

Type

Unclassified

Intellectual base

Unclassified

Year

1983

DOI

10.1016/0306-4522(83)90024-6

Link

https://doi.org/10.1016/0306-4522(83)90024-6

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Domain-specific

• Somatotopy
  • The map is established developmentally through molecular axon-guidance mechanisms and activity-dependent competition between afferent fibres, and it is plastic across the lifespan: amputation of a digit leads within weeks to expansion of neighbouring digit representations into the vacated cortical territory; intensive instrumental practice expands the representation of the practicing fingers relative to others; in chronic pain, the cortical representation of the affected body region can show systematic distortion

    This sourceMerzenich and colleagues' deafferentation experiment, in which neighbouring skin-field representations expand to completely occupy vacated cortex in areas 3b and 1 of adult monkeys with topography preserved; the lesion is median nerve section rather than digit amputation, the time course is two to nine months, and the practice and chronic-pain clauses are not from this paper.

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