Evaluating Treatment Protocols to Prevent Antibiotic Resistance¶
Bonhoeffer, S., Lipsitch, M., & Levin, B. R. (1997). Evaluating Treatment Protocols to Prevent Antibiotic Resistance. Proceedings of the National Academy of Sciences, 12106-12111.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Vaccine Escape
- The compression also sorts the interventions into a stable family. Combination barriers — multiple uncorrelated filters applied simultaneously so escape requires evading all at once (drug cocktails, defense-in-depth, layered herbicide programs, multiple independent AML indicators).
This sourceCombination therapy requiring simultaneous resistance multiplies escape probability down; analysis of multi-drug protocols.
Supported in partVerified against the work's full text
Supports that combination antibiotic therapy generally limits resistance, but covers none of the other listed instances or the 'stable family of interventions' framing.
“However, treatment of all patients with a combination of antibiotics is in most cases the optimal treatment strategy.”
- The compression also sorts the interventions into a stable family. Combination barriers — multiple uncorrelated filters applied simultaneously so escape requires evading all at once (drug cocktails, defense-in-depth, layered herbicide programs, multiple independent AML indicators).
Verification¶
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Registry ID ref:bf374804a8ab · see in the full table