Evaluating Treatment Protocols to Prevent Antibiotic Resistance¶
Bonhoeffer, S., Lipsitch, M., & Levin, B. R. (1997). Evaluating Treatment Protocols to Prevent Antibiotic Resistance. Proceedings of the National Academy of Sciences, 12106-12111.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Vaccine Escape
- The compression also sorts the interventions into a stable family. Combination barriers — multiple uncorrelated filters applied simultaneously so escape requires evading all at once (drug cocktails, defense-in-depth, layered herbicide programs, multiple independent AML indicators).
This sourceCombination therapy requiring simultaneous resistance multiplies escape probability down; analysis of multi-drug protocols.
- The compression also sorts the interventions into a stable family. Combination barriers — multiple uncorrelated filters applied simultaneously so escape requires evading all at once (drug cocktails, defense-in-depth, layered herbicide programs, multiple independent AML indicators).
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