Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings¶
Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (1997). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews, 23(1–3), 1-3.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Domain-specific¶
- Lipinski's Rule of Five
- The original 1997 publication places the rule in the discovery setting and phrases its conclusion as poor absorption or permeation becoming more likely.
This sourceExact four alert values, alternative MLogP 4.15, discovery/development distinction and probabilistic language come from the abstract.
- The original 1997 publication places the rule in the discovery setting and phrases its conclusion as poor absorption or permeation becoming more likely.
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