Group Sequential Methods with Applications to Clinical Trials¶
Jennison, C., & Turnbull, B. W. (2000). Group Sequential Methods with Applications to Clinical Trials. Chapman & Hall.
Cited by¶
2 citations across 2 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Optimal Stopping Rule
- In statistics, sequential analysis and group-sequential clinical-trial designs with futility and efficacy boundaries operationalize stopping for ethical and resource reasons.
This sourceStandard reference on sequential analysis and group-sequential designs with interim looks, accumulating test statistics, and futility/efficacy stopping boundaries.
- In statistics, sequential analysis and group-sequential clinical-trial designs with futility and efficacy boundaries operationalize stopping for ethical and resource reasons.
- Termination Condition
- The branch-and-bound termination vocabulary — gap closure, bound improvement — maps directly to group-sequential trial design with its efficacy and futility bounds, with parallel mathematical structure and parallel optional-stopping pathologies, so an algorithm designer's stopping intuition becomes a trial statistician's.
This sourceStandard reference for group-sequential designs with efficacy and futility boundaries and a maximum sample size as the termination structure.
- The branch-and-bound termination vocabulary — gap closure, bound improvement — maps directly to group-sequential trial design with its efficacy and futility bounds, with parallel mathematical structure and parallel optional-stopping pathologies, so an algorithm designer's stopping intuition becomes a trial statistician's.
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