Hemorrhage During Warfarin Therapy Associated With Cotrimoxazole and Other Urinary Tract Anti-infective Agents¶
Fischer, H. D., Juurlink, D. N., Mamdani, M. M., Kopp, A., & Laupacis, A. (2010). Hemorrhage During Warfarin Therapy Associated With Cotrimoxazole and Other Urinary Tract Anti-infective Agents. Archives of Internal Medicine.
Cited by¶
1 citation across 1 artifact.
Domain-specific¶
- Adverse Drug Event
- A classic precipitating interaction: a patient stable on warfarin is prescribed co-trimoxazole (which contains sulfamethoxazole) for an infection; sulfamethoxazole inhibits the CYP2C9 enzyme that clears warfarin, warfarin levels rise, the INR climbs well above range, and a gastrointestinal or intracranial bleed follows — even though every prescription was written and taken correctly
Supported in partVerified against the source
- A classic precipitating interaction: a patient stable on warfarin is prescribed co-trimoxazole (which contains sulfamethoxazole) for an infection; sulfamethoxazole inhibits the CYP2C9 enzyme that clears warfarin, warfarin levels rise, the INR climbs well above range, and a gastrointestinal or intracranial bleed follows — even though every prescription was written and taken correctly
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:c9ce7fbbb5f2 · see in the full table