Drug Discovery¶

Drews, J. (2000). Drug Discovery: A Historical Perspective. Science, 1960-1964.

Type: Journal article
Intellectual base: Primary research
Year: 2000
Pages: 1960-1964
DOI: 10.1126/science.287.5460.1960
DOI registrant: American Association for the Advancement of Science
Link: https://doi.org/10.1126/science.287.5460.1960
Cited from: computer_science

Cited by¶

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes¶

Abstract Data Type
- The pattern ports further. Enzyme functional roles into pharmacology: the function-versus-mechanism split transferred into drug design, where targets are specified by functional role and candidate molecules are evaluated against the functional contract.
  This sourceDescribes the shift to target-based drug discovery, in which a drug target is specified by its functional/molecular role and candidate molecules are evaluated against that functional specification.
  
  Supported in partVerified against the publisher's abstract
  
  The abstract supports only the generic half: drug research is increasingly guided by pharmacology and by molecular/genomic dissection of disease to locate 'points of attack'.
  
  “Genome sciences, combined with bioinformatic tools, allow us to dissect the genetic basis of multifactorial diseases and to determine the most suitable points of attack for future medicines, thereby increasing the number of treatment options.”
  From the publisher's abstract.
  
  Read by an automated reader; not a human review. How support was checked

Verification¶

Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.

Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.

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Registry ID ref:cafe26c4454d · see in the full table