Addiction to Oncogenes—the Achilles Heal of Cancer.

Weinstein, I. B. (2002). Addiction to Oncogenes—the Achilles Heal of Cancer. Science, 63-64.

Type

Journal article

Intellectual base

Primary research

Year

2002

DOI

10.1126/science.1073096

Link

https://doi.org/10.1126/science.1073096

Cited from

systems_cybernetics

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Dependency Distribution Concentration
  • In physiology, single-pathway metabolic dependence and single-receptor signaling concentrate function so that antagonizing one target collapses downstream behavior.

    This sourceEstablishes oncogene addiction — a tumor's survival concentrated on a single pathway so that antagonizing one target collapses downstream behavior — the physiology/single-pathway-dependence instance.

Verification

This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.

Registry ID ref:cd7a09b53228 · see in the full table