Addiction to Oncogenes—the Achilles Heal of Cancer.

Weinstein, I. B. (2002). Addiction to Oncogenes—the Achilles Heal of Cancer. Science, 63-64.

Type

Journal article

Intellectual base

Primary research

Year

2002

Pages

63-64

DOI

10.1126/science.1073096

DOI registrant

American Association for the Advancement of Science

Link

https://doi.org/10.1126/science.1073096

Cited from

systems_cybernetics

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Dependency Distribution Concentration
  • In physiology, single-pathway metabolic dependence and single-receptor signaling concentrate function so that antagonizing one target collapses downstream behavior.

    This sourceEstablishes oncogene addiction — a tumor's survival concentrated on a single pathway so that antagonizing one target collapses downstream behavior — the physiology/single-pathway-dependence instance.

Verification

Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.

Does it back the claim? Not recorded. The single citation of this work carries no recorded support check.

Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.

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Registry ID ref:cd7a09b53228 · see in the full table