Statistical Issues in Drug Development

Senn, S. (2007). Statistical Issues in Drug Development. Wiley.

Type

Book

Intellectual base

Textbook

Year

2007

DOI

10.1002/9780470723586

ISBN

9780470018774

Link

https://doi.org/10.1002/9780470723586

Cited from

statistics_experimental_design

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Counterfactual Subtraction
  • Pharmacology and clinical measurement: placebo-subtracted drug effect; baseline-subtracted pharmacokinetic curve; pre/post deltas in single-subject studies.

    This sourceEstablishes placebo-corrected change-from-baseline (the ΔΔ estimator) and baseline adjustment as standard clinical-pharmacology/trials practice, where the placebo arm is the subtracted counterfactual baseline.

Verification

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