Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias¶
KLÉBER, A. G., & RUDY, Y. (2004). Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias. Physiological Reviews, 84(2), 431-488.
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Mechanisms¶
- Refractory Period
- The classic misuse is porting the biological guarantee into a software rate-limiter and assuming the same hard safety — but an engineered lockout that is set too long turns a protective refractory period into dropped legitimate events, the timing analogue of a cardiac arrhythmia's vulnerable window.
This sourceExplains the cardiac vulnerable window during the relative refractory period in which precisely timed stimulation can produce unidirectional block and reentry.
- The classic misuse is porting the biological guarantee into a software rate-limiter and assuming the same hard safety — but an engineered lockout that is set too long turns a protective refractory period into dropped legitimate events, the timing analogue of a cardiac arrhythmia's vulnerable window.
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