The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs¶
Reimer. (1977). The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs. Circulation.
Cited by¶
1 citation across 1 artifact.
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Domain-specific¶
- Hypoxia
- Neurons, with high baseline metabolic demand and minimal glycogen stores, suffer irreversible injury within minutes of complete oxygen deprivation; cardiac muscle tolerates roughly thirty minutes before infarction of the ischaemic core
This sourceAn experimental study quantitating myocardial necrosis against occlusion duration, showing subendocardial necrosis after 40 minutes of coronary occlusion progressing as a wavefront.
Supported in partVerified against the publisher's abstract
“Irreversible ischemic myocardial cell injury developes in an increasing number of cells as the duration of coronary occlusion is prolonged.”
- Neurons, with high baseline metabolic demand and minimal glycogen stores, suffer irreversible injury within minutes of complete oxygen deprivation; cardiac muscle tolerates roughly thirty minutes before infarction of the ischaemic core
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