Overcoming the Challenges in Administering Biopharmaceuticals¶
Mitragotri, S., Burke, P. A., & Langer, R. (2014). Overcoming the Challenges in Administering Biopharmaceuticals: Formulation and Delivery Strategies. Nature Reviews Drug Discovery, 13(9), 655-672.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Bioavailability
- Move the application point closer to the locus: targeted drug delivery, point-of-need education, last-mile aid, just-in-time inventory.
This sourceReviews targeted and localized delivery strategies that raise drug concentration at the site of action while lowering systemic dose — moving the application point closer to the locus raises the effective fraction.
Supported in partVerified against the work's full text
Review supports targeted and local drug delivery as a way to concentrate biopharmaceuticals at specific tissues; it says nothing of education, aid or inventory.
“The local delivery of conventional formulations is the simplest option for targeting specific tissues”
- Move the application point closer to the locus: targeted drug delivery, point-of-need education, last-mile aid, just-in-time inventory.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
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Registry ID ref:d72e6cfc2acb · see in the full table