Microbiological Effects of Sublethal Levels of Antibiotics.

Andersson, D. I., & Hughes, D. (2014). Microbiological Effects of Sublethal Levels of Antibiotics. Nature Reviews Microbiology, 12(7), 465-478.

Type

Journal article

Intellectual base

Primary research

Year

2014

Volume

12

Issue

7

Pages

465-478

DOI

10.1038/nrmicro3270

DOI registrant

Springer Nature

Link

https://doi.org/10.1038/nrmicro3270

Cited from

systems_cybernetics

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Sanctuary Effect
  • In antimicrobial and pesticide resistance it is the untreated niche (gut flora, soil microbiome, biofilm) within which resistant strains persist and re-emerge.

    This sourceDocuments how untreated or sub-inhibitory niches sustain and re-seed resistant bacterial populations.

    Supported in partVerified against the publisher's abstract

    The abstract backs only that subinhibitory antibiotic concentrations select for bacterial resistance and accelerate its emergence and spread; it says nothing of untreated niches, biofilms, gut flora, soil, pesticides or vaccination.

    “In this Review, we discuss the ecology of antibiotics and the ability of subinhibitory concentrations to select for bacterial resistance. We also consider the effects of low-level drug exposure on bacterial physiology, including the generation of genetic and phenotypic variability, as well as the ability of antibiotics to function as signalling molecules. Together, these effects accelerate the emergence and spread …”

    Read by an automated reader; not a human review. How support was checked

Verification

Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.

Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.

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Registry ID ref:d76348c91625 · see in the full table