Pattern formation by lateral inhibition with feedback¶
Collier, J. R., Monk, Maini, & Lewis, J. H. (1996). Pattern formation by lateral inhibition with feedback: a mathematical model of Delta-Notch intercellular signalling. Journal of Theoretical Biology, 183(4), 429-446.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Lateral Inhibition
- Developmental biology (non-obvious): Notch-Delta signaling lets a cell that begins adopting a particular fate inhibit its immediate neighbors from adopting the same fate, producing salt-and-pepper differentiation patterns and regular spacing of structures such as sensory bristles or hair cells.
This sourceFoundational model of contact-mediated lateral inhibition in development: a cell adopting a fate inhibits its immediate neighbors via Notch-Delta feedback, producing salt-and-pepper differentiation and regularly spaced structures (e.g., sensory bristles) with no central planner.
- Developmental biology (non-obvious): Notch-Delta signaling lets a cell that begins adopting a particular fate inhibit its immediate neighbors from adopting the same fate, producing salt-and-pepper differentiation patterns and regular spacing of structures such as sensory bristles or hair cells.
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