Analogous Enzymes¶
Galperin, M. Y., Walker, D. R., & Koonin, E. V. (1998). Analogous Enzymes: Independent Inventions in Enzyme Evolution. Genome Research, 779-790.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Abstract Data Type
- Organisational design — job descriptions and role specifications separate the role (expected behaviour, deliverables, decision rights) from the incumbent, so the organisation survives individual departures. Biology — enzyme and receptor functional roles specified by reaction or binding type independent of molecular implementation, with multiple distinct molecules occupying the same functional role.
This sourceDocuments non-homologous (analogous) enzymes — structurally distinct molecules with different folds that independently occupy the same catalytic functional role (same EC number), the biological case of multiple implementations conforming to one functional contract.
Supported in partVerified against the work's full text
Galperin et al. show that structurally unrelated enzymes can fill the same catalytic role (same EC number), supporting the enzyme half; receptors and binding types are not covered.
“Analogous enzymes were therefore identified as enzymes with the same EC numbers that had no detectable sequence similarity to each other.”
- Organisational design — job descriptions and role specifications separate the role (expected behaviour, deliverables, decision rights) from the incumbent, so the organisation survives individual departures. Biology — enzyme and receptor functional roles specified by reaction or binding type independent of molecular implementation, with multiple distinct molecules occupying the same functional role.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:d95ad6e6798e · see in the full table