Clinical Pharmacokinetics of Ethanol¶
Holford, N. H. G. (1987). Clinical Pharmacokinetics of Ethanol. Clinical Pharmacokinetics, 13(5), 273-292.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Clearance Rate
- Ethanol exposes the contrasting zero-order regime: the clearing enzyme (alcohol dehydrogenase) saturates at modest concentrations, so clearance is capped at a fixed maximum rate and any intake above that cap accumulates with no finite steady state — which is exactly why "modest" extra drinks produce disproportionately high and sustained blood-alcohol levels.
This sourceDocuments zero-order (capacity-limited) ethanol elimination via saturated alcohol dehydrogenase, so intake above the cap accumulates with no finite steady state.
- Ethanol exposes the contrasting zero-order regime: the clearing enzyme (alcohol dehydrogenase) saturates at modest concentrations, so clearance is capped at a fixed maximum rate and any intake above that cap accumulates with no finite steady state — which is exactly why "modest" extra drinks produce disproportionately high and sustained blood-alcohol levels.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Not recorded. The single citation of this work carries no recorded support check.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:da7f50dd9af5 · see in the full table