Defining hormesis¶
Calabrese, E. J., & Baldwin, L. A. (2002). Defining hormesis. Human & Experimental Toxicology, 21(2), 91-97.
Cited by¶
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Primes¶
- Stressor Induced Adaptation
- The same shape is named hormesis in toxicology and progressive overload in exercise physiology, and across all three the structural logic is identical: a sub-injurious dose of stress provokes an adaptive response that overshoots the original baseline, leaving the system stronger than before it was perturbed.
This sourceDocuments the biphasic (inverted-U) dose-response as a generalizable adaptive shape across pharmacology, toxicology, and cell biology, supplying the single three-regime curve (sub-threshold, strengthening band, damage) shared by desirable difficulties, hormesis, and progressive overload.
- The same shape is named hormesis in toxicology and progressive overload in exercise physiology, and across all three the structural logic is identical: a sub-injurious dose of stress provokes an adaptive response that overshoots the original baseline, leaving the system stronger than before it was perturbed.
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