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Hsp90 as a Capacitor for Morphological Evolution

Rutherford, S. L., & Lindquist, S. (1998). Hsp90 as a Capacitor for Morphological Evolution. Nature.

Type
Journal article
Intellectual base
Primary research
Year
1998
DOI
10.1038/24550
DOI registrant
Springer Nature
Link
https://doi.org/10.1038/24550
Cited from
biology_ecology

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

  • Selection-Visibility Gate
    • If it does not, what looked like a gate was ordinary attrition, noise, or an artefact of how the survivors were later described.

      This sourceReduces a buffering modifier while leaving the standing variation and the selective regime in place, and finds previously masked phenotypic variation expressed and available to selection.

      Supported in partVerified against the publisher's abstract

      The abstract shows Hsp90 buffers cryptic variation whose release is selectable and persists without Hsp90; it says nothing about the clause naming attrition, noise, or description artefacts.

      “Hsp90 buffers this variation, allowing it to accumulate under neutral conditions. When Hsp90 buffering is compromised, for example by temperature, cryptic variants are expressed and selection can lead to the continued expression of these traits, even when Hsp90 function is restored.”

      From the publisher's abstract.

      Read by an automated reader; not a human review. How support was checked

Verification

Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.

Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.

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Registry ID ref:dc852f1b5eec · see in the full table