LTP and LTD

Malenka, R. C., & Bear, M. F. (2004). LTP and LTD: An embarrassment of riches. Neuron, 44(1), 5-21.

Type

Journal article

Intellectual base

Primary research

Year

2004

Link

https://doi.org/10.1016/j.neuron.2004.09.012matched

Cited from

pharmacology_toxicology

Cited by

1 citation across 1 artifact.

Primes

• Potentiation
  • The response shift reflects internal sensitization of the responding substrate—receptor up-regulation increasing the number of available binding sites, synaptic strengthening through insertion of additional receptors (AMPA insertion at potentiated synapses), signal-transduction amplification via kinase cascades and phosphorylation, or pathway priming in which a first stimulus prepares intracellular machinery for rapid amplified response to a second, mechanisms Malenka and Bear (2004) catalogue as the molecular foundation of LTP.

Verification

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Registry ID ref:e5f011cf821e · see in the full table