The New Frontier of Genome Engineering with CRISPR-Cas9¶
Doudna, J. A., & Charpentier, E. (2014). The New Frontier of Genome Engineering with CRISPR-Cas9. Science, 346(6213).
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Defect
- Carried into biology, point mutations are defects with macroscopic genetic consequences, and gene therapy and CRISPR are defect-engineering interventions on the genome's regular structure.
This sourceReviews programmable RNA-guided CRISPR-Cas9 genome editing — targeted intervention on a specific genomic locus, i.e., defect engineering on the genome's regular structure rather than redesigning the bulk.
- Carried into biology, point mutations are defects with macroscopic genetic consequences, and gene therapy and CRISPR are defect-engineering interventions on the genome's regular structure.
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Registry ID ref:e7505b0e4959 · see in the full table