Scale-Up Methodology for Chemical Processes¶
Euzen, J., Trambouze, P., & Wauquier, J. (1993). Scale-Up Methodology for Chemical Processes.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Pilot To Scale Transition
- Enterprise software: proof-of-concept deployments in friendly business units that succeed because an executive sponsor protects them, then fail to generalise without that protection. Clinical translation: bench and Phase-1 evidence that does not predict Phase-3 outcomes in a heterogeneous patient population. Manufacturing scale-up: chemical processes where reactor geometry, mixing, and heat-transfer ratios change qualitatively from bench to pilot plant to production plant.
This sourceStandard text on reactor scale-up: heat generation scaling with volume while removal scales with surface area, the falling surface-to-volume ratio, preservation of dimensionless transport ratios, and the necessity of an intermediate pilot-plant tier.
- Enterprise software: proof-of-concept deployments in friendly business units that succeed because an executive sponsor protects them, then fail to generalise without that protection. Clinical translation: bench and Phase-1 evidence that does not predict Phase-3 outcomes in a heterogeneous patient population. Manufacturing scale-up: chemical processes where reactor geometry, mixing, and heat-transfer ratios change qualitatively from bench to pilot plant to production plant.
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Registry ID ref:ea3699e92829 · see in the full table