Design and Analysis of Cross-Over Trials¶
Jones, B., & Kenward, M. G. (2014). Design and Analysis of Cross-Over Trials. Chapman & Hall.
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Primes¶
- Washout Failure
- In crossover clinical trials, each patient receives treatment \(A\), then treatment \(B\), and serves as their own control.
This sourceCanonical text on crossover-trial design: setting washout to multiple half-lives, counterbalancing treatment order, and switching to parallel-group designs when carryover is intractable.
- In crossover clinical trials, each patient receives treatment \(A\), then treatment \(B\), and serves as their own control.
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