Health Risks from Exposure to Low Levels of Ionizing Radiation¶
National Research Council, Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation. (2006). Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2. National Academies Press.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Dose-Response Relationship
- Dose-response relationships appear in pharmacology (drug potency, efficacy, and dosing regimen design) as the foundational quantitative framework; in toxicology (carcinogen assessment, chemical exposure limits, no-observed-adverse-effect levels); in ecotoxicology (pollutant effects on species and ecosystems); in radiation biology (linear no-threshold versus threshold models of radiation damage), where the National Research Council's BEIR VII report (2006) marshals epidemiological and biological evidence to argue that risk of solid cancers from low-dose ionizing radiation rises linearly with dose without a threshold; in environmental health (air quality standards, lead exposure); in materials engineering (stress-strain curves share the structural logic); in behavioral psychology and economics (incentive-response relationships, diminishing marginal utility); and in clinical trial design (dose-finding studies, pharmacodynamic modeling).
This sourcePooled epidemiological/biological review supporting the linear-no-threshold model; supports D47-025 (low-dose ionizing-radiation solid-cancer risk rising linearly without a threshold).
- Dose-response relationships appear in pharmacology (drug potency, efficacy, and dosing regimen design) as the foundational quantitative framework; in toxicology (carcinogen assessment, chemical exposure limits, no-observed-adverse-effect levels); in ecotoxicology (pollutant effects on species and ecosystems); in radiation biology (linear no-threshold versus threshold models of radiation damage), where the National Research Council's BEIR VII report (2006) marshals epidemiological and biological evidence to argue that risk of solid cancers from low-dose ionizing radiation rises linearly with dose without a threshold; in environmental health (air quality standards, lead exposure); in materials engineering (stress-strain curves share the structural logic); in behavioral psychology and economics (incentive-response relationships, diminishing marginal utility); and in clinical trial design (dose-finding studies, pharmacodynamic modeling).
Verification¶
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Registry ID ref:f1c346531929 · see in the full table