ICH E9(R1), Addendum on Estimands and Sensitivity Analysis in Clinical Trials¶
International Council for Harmonisation. (2019). ICH E9(R1), Addendum on Estimands and Sensitivity Analysis in Clinical Trials.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- External Analytic Challenge
- A challenge with identical content delivered at the end of the trial produces a critique, and delivered here produces a different trial. Mapped back: the protocol is the revisable work, the programme's accumulated history is the authoring frame, the unaffiliated reviewers are the outside station while their access to the prior reports is what makes them competent rather than merely independent, the estimand and dropout questions are probes rather than reactions, the response table is the recorded obligation, and first dose is the threshold the whole arrangement is scheduled against.
This sourceSpecifies the estimand and intercurrent-event questions a trial protocol must settle before the trial starts, which is what makes them probes rather than post-hoc critique.
- A challenge with identical content delivered at the end of the trial produces a critique, and delivered here produces a different trial. Mapped back: the protocol is the revisable work, the programme's accumulated history is the authoring frame, the unaffiliated reviewers are the outside station while their access to the prior reports is what makes them competent rather than merely independent, the estimand and dropout questions are probes rather than reactions, the response table is the recorded obligation, and first dose is the threshold the whole arrangement is scheduled against.
Verification¶
Does it exist? Not checked yet. This entry carries no identifier to resolve. It was extracted from the citation as written in the article, normalized, and deduplicated against the rest of the registry.
Does it back the claim? Not recorded. The single citation of this work carries no recorded support check.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:f33cdc528185 · see in the full table