Biopharmaceutics and Relevant Pharmacokinetics¶
Wagner, J. G. (1971). Biopharmaceutics and Relevant Pharmacokinetics.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- PK/PD Modeling (Pharmacokinetics / Pharmacodynamics)
- Formal case — vancomycin AUC/MIC-targeted dosing: Vancomycin efficacy against methicillin-resistant Staphylococcus aureus correlates with the ratio of area-under-the-concentration-curve (AUC) over 24 hours to the minimum inhibitory concentration (MIC), targeting AUC24/MIC ≥ 400, applying the foundational biopharmaceutic and pharmacokinetic apparatus systematized by Wagner (1971).
This sourceDrug Intelligence Publications. Foundational unification of biopharmaceutics and pharmacokinetics: develops the AUC, clearance, and dose-AUC relationships that ground AUC/MIC-targeted dosing for vancomycin and related antibiotics.
- Formal case — vancomycin AUC/MIC-targeted dosing: Vancomycin efficacy against methicillin-resistant Staphylococcus aureus correlates with the ratio of area-under-the-concentration-curve (AUC) over 24 hours to the minimum inhibitory concentration (MIC), targeting AUC24/MIC ≥ 400, applying the foundational biopharmaceutic and pharmacokinetic apparatus systematized by Wagner (1971).
Verification¶
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Registry ID ref:f5e286a5116f · see in the full table