Pharmacokinetic-Pharmacodynamic Modeling and Simulation¶
Bonate, P. L. (2011). Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Springer.
Cited by¶
1 citation across 1 artifact.
Primes¶
- PK/PD Modeling (Pharmacokinetics / Pharmacodynamics)
- PK/PD is specifically the time-resolved coupled model, as Bonate (2011) emphasizes in his treatment of pharmacokinetic-pharmacodynamic modeling and simulation; static dose-response is a degenerate special case (valid only when PK time course is fast relative to response time course and effect equilibrates rapidly with plasma levels).
Supported in partVerified against the publisher's abstract
Confirms only that Bonate (2011) is a comprehensive PK/PD modeling-and-simulation book; its blurb never mentions time-resolved coupled models or a degenerate static dose-response.
“The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models.”
- PK/PD is specifically the time-resolved coupled model, as Bonate (2011) emphasizes in his treatment of pharmacokinetic-pharmacodynamic modeling and simulation; static dose-response is a degenerate special case (valid only when PK time course is fast relative to response time course and effect equilibrates rapidly with plasma levels).
Verification¶
Does it exist? Not checked yet. This entry carries no identifier to resolve. It was extracted from the citation as written in the article, normalized, and deduplicated against the rest of the registry.
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Registry ID ref:f8f85d64d587 · see in the full table