Choice of Control Group and Related Issues in Clinical Trials¶
International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. (2000). Choice of Control Group and Related Issues in Clinical Trials.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Mechanisms¶
- Standard-Care Comparator Specification
- The specification also notes that a study powered against this stronger comparator needs a larger sample
This sourceExplains that active-control trials often require large sample sizes because the relevant treatment difference or noninferiority margin is small.
- The specification also notes that a study powered against this stronger comparator needs a larger sample
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Registry ID ref:fb104f58e037 · see in the full table