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Tensions in Practice: A small screening design in tension with separating effects

A toy experiment with three two-level factors

Factors A, B and C each take levels −1 and +1. A four-run design keeps only combinations where A = B × C. On those runs, the candidate response laws Y = 10 + A and Y = 10 + B × C give identical predictions. Running all eight combinations separates the two laws because A and B × C disagree on the added rows. The reduced design costs fewer runs, but it cannot decide which of those terms produced a response.

Screen with fewer runs

Use four controlled combinations when runs are expensive.

Separate rival effects

Distinguish an A contribution from a B-by-C interaction.

Why these aims pull against each other

The fractional design makes two analysis columns identical. Separation requires more combinations or an explicit assumption about one of the effects.

Compare the arrangements

Run the selected half

Use the four Yes rows satisfying A = B × C.

Four runs with A = B × C
AB × CRun?
− − −−11No
− − +−1−1Yes
− + −−1−1Yes
− + +−11No
+ − −11Yes
+ − +1−1No
+ + −1−1No
+ + +11Yes
What it protects
Only four experimental runs are required.
What it costs
A and B × C are aliased: their separate coefficients cannot be recovered from these runs alone.
When it fits
Fits screening when the alias is acceptable and any neglect of the interaction is explicitly justified.

Illustration note: This is an exact equality of design columns, not a noisy failure to detect an effect. No interaction is silently assumed zero.

Run the full design

Add the four previously omitted combinations.

All eight combinations
AB × CRun?
− − −−11Yes
− − +−1−1Yes
− + −−1−1Yes
− + +−11Yes
+ − −11Yes
+ − +1−1Yes
+ + −1−1Yes
+ + +11Yes
What it protects
The A and B × C columns now differ, separating the stated response laws.
What it costs
Eight runs are needed rather than four.
When it fits
Fits when distinguishing this interaction from A matters and all combinations are feasible.

Illustration note: The table establishes algebraic separation. With real noise, precision and replication still matter.

What this illustration does—and does not—establish

The source supplies the structural tension; the invented example makes one relation inspectable. Costs and conditions are part of each arrangement, not exceptions to a universal recommendation.

  • The row label gives A, B, C signs in that order. The two candidate laws are invented, not observed outcomes.
  • A full design without replication does not by itself establish a noise model or precise effect estimates.
  • Controlled factor settings and the selected alias are declared; this is not a claim about arbitrary observational records.

Source entries

Factorial Design

Prime · Source of the tension

The canonical tension motivates this comparison. The setting, finite values and arrangements are declared editorial illustrations, not measured findings.

Interaction discovery versus run-count growth

The tension is how aggressively to fractionate: too little fractionation leaves the design infeasible; too much fractionation creates "aliasing" where main effects are confounded with two-way interactions, potentially producing misleading results.

Read the source section

The source operation

(1) A factorial design varies two or more factors simultaneously at multiple levels within a single integrated experiment, so that every combination of factor levels (or a carefully balanced subset) is observed, rather than studying one factor at a time while holding others fixed.

Read the source section